Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

mouse
Strain Name:C57BL/6JSmo-Sh3rf2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190449
Disease Connection:autism spectrum disorder
mouse
Strain Name:C57BL/6JSmo-Sh3tc1em1Smoc
Strain State:Developing | Cat. NO.:NM-KO-254090
mouse
Strain Name:C57BL/6JSmo-Sh3tc2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201059
Disease Connection:Charcot-Marie-Tooth disease type 4C
mouse
Strain Name:C57BL/6Smoc-Sh3Yl1em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6Smoc-Shank1em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Shank3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-241043
Disease Connection:autism spectrum disorder, Phelan-McDermid syndrome
mouse
Strain Name:C57BL/6JSmo-Sharpinem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2104118
mouse
Strain Name:C57BL/6JSmo-Shbgem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-205418
Research Application:secreted protein
mouse
Strain Name:C57BL/6JSmo-Shc1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-231739
mouse
Strain Name:C57BL/6Smoc-Shc2em1Smoc
Strain State:Developing | Cat. NO.:TBD
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