Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Sfxn2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241058
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Strain Name：C57BL/6JSmo-Sfxn3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200481
Research Application：Therapeutic antibody target
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Strain Name：C57BL/6Smoc-Sgcaem1Smoc
Strain State：Developing | Cat. NO.：TBD
Disease Connection：autosomal recessive limb-girdle muscular dystrophy type 2D
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Strain Name：NOD.Cg-PrkdcscidIl2rgem1Sgcaem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-232211
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Strain Name：C57BL/6JSmo-Sgcbem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201058
Disease Connection：autosomal recessive limb-girdle muscular dystrophy type 2E
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Strain Name：C57BL/6JSmo-Sgcdem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201205
Disease Connection：dilated cardiomyopathy 1L
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Strain Name：C57BL/6JSmo-Sgceem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210227
Disease Connection：myoclonic dystonia 11
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Strain Name：C57BL/6JSmo-Sgcgem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201792
Disease Connection：autosomal recessive limb-girdle muscular dystrophy type 2C
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