Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Rpeem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-240256
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Strain Name：C57BL/6JSmo-Rpe65em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2104746
Disease Connection：Leber congenital amaurosis 2
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Strain Name：C57BL/6JSmo-RpgremSmoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220487
Disease Connection：X-linked cone-rod dystrophy 1
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Strain Name：C57BL/6JSmo-Rpgrip1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2108670
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Strain Name：C57BL/6Smoc-Rpgrip1Lem1Smoc
Strain State：Developing | Cat. NO.：TBD
Disease Connection：Meckel syndrome
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Strain Name：C57BL/6JSmo-Rph3Aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191027
Research Application：Nervous system, release of neurotransmitters and transport of synaptic vesicles; lymphocyte funnel pituitary (LINH)
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