hIL5/hIL5R(3)

Nomenclature

C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc

Cat. NO.

NM-HU-220011

Strain State

Repository Live

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Model Description

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

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Fig1. Expression of hIL5R on Bone marrow-derived eosinophils in hIL5/hIL5R(3) dKI mice.

Note: Eosinophils were derived from bone marrow cells through culture with rmSCF, rmFLT-3L, and rmlL-5.

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