hHLA-DPB1*04: 01

Nomenclature

C57BL/6Smoc-H2-Ab1em1(hHLA-DPB1*04: 01)/Smoc

Cat. NO.

NM-HU-210011

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
H2-Ab1

Synonyms

IAb; Ia2; Ia-2; Abeta; H-2Ab; H2-Ab; Rmcs1; I-Abeta

NCBI ID

14961

MGI ID

103070

Ensembl ID

ENSMUSG00000073421

Pubmed

H2-Ab1

Human Ortholog

HLA-DQB2

Model Description

The endogenous mice H2-Ab1 gene was replaced by human HLA-DPB1*04:01 gene.
Research Application：inmmue therapy；drug screening

Validation Data

image.png

Fig1. Detection of HLA-DPB1*04:01 expression in spleen by RT-PCR. Wild type: only one band at 372 bp with primers F1/R1(mH2-Ab1);Heterozygous: one band at 372 bp with primers F1/R1(mH2-Ab1) and one band at 362 bp with primers F2/R2(hHLA-DPB1*04:01); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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