hIL3/hCSF2

Nomenclature

C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc

Cat. NO.

NM-HU-190065

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol

Synonyms

BPA Csfmu HCGF Il-3 MCGF PSF， CSF， Csfgm， GMCSF， Gm-CSf， MGI-IGM

NCBI ID

16187，12981

MGI ID

96552，1339752

Ensembl ID

ENSMUSG00000018914，ENSMUSG00000018916

Pubmed

Human Ortholog

IL3，CSF2

Model Description

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig.1 Detection of mCSF2(A) and hCSF2(B) expression in serum by ELISA(n=3). 

Abbr. HO, homozygous; WT, wild type; N.D. not detected

Note.hIL3/hCSF2 and C57BL/6 mice were i.p. injected with LPS for 2h.

image.png

Fig.2 Detection of mIL3(A) and hIL3(B) expression in splenocyte by ELISA(n=3). 

Abbr. HO, homozygous; WT, wild type; N.D. not detected.

Note. Splenocyte were stimulated with ConA and IL2 in vitro for 48h.


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