MIA PaCa-2-hCLDN18.2
Strain Information
Validation Data
Ⅰ.In vitro Expression of MIA Paca-2-hCLDN18.2 cell line
Figure 1. hCLDN18.2 expression in MIA Paca-2 and MIA Paca-2-hCLDN18.2 cell lines
Ⅱ.Characterization of in vivo growth kinetics
Cells were subcutaneously inoculated into the NMG mice.
Figure 2. Tumor growth curve of MIA Paca-2-hCLDN18.2 xenograft model model (n=5)
Figure 3. Body weight change of MIA Paca-2-hCLDN18.2 xenograft model model (n=5)
Ⅲ.Expression of hCLDN18.2 protein in tumors
To verify the hCLDN18.2 protein expression, the tumors were dissected and separated for single cell suspension.
Figure 4. The expression of hCLDN18.2 in humanized modified tumors by FACS
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreAt GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
