MIA PaCa-2-hCLDN18.2
Strain Information
Validation Data
Ⅰ.In vitro Expression of MIA Paca-2-hCLDN18.2 cell line
Figure 1. hCLDN18.2 expression in MIA Paca-2 and MIA Paca-2-hCLDN18.2 cell lines
Ⅱ.Characterization of in vivo growth kinetics
Cells were subcutaneously inoculated into the NMG mice.
Figure 2. Tumor growth curve of MIA Paca-2-hCLDN18.2 xenograft model model (n=5)
Figure 3. Body weight change of MIA Paca-2-hCLDN18.2 xenograft model model (n=5)
Ⅲ.Expression of hCLDN18.2 protein in tumors
To verify the hCLDN18.2 protein expression, the tumors were dissected and separated for single cell suspension.
Figure 4. The expression of hCLDN18.2 in humanized modified tumors by FACS
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