MC38-hFOLR1/hCD47(2)

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Strain Information

Cell Line

MC38-Igs2em(hFOLR1)Cd47tm(hCD47)Smoc

Cat. NO.

NM-S13-TM87

Model Description

FOLR1/CD47 gene humanized mouse colon adenocarcinoma cell.

Strain State

Validation of tumorigenic capacity completed

Validation Data

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Fig1. Analysis of hFOLR1 and hCD47 expression in in vitro cultured MC38-hFOLR1/hCD47 cells by FACS.

image.pngFig2. In vivo validation of MC38-hFOLR1/hCD47 in C57BL/6 mice. C57BL/6 mice were inoculated with MC38-hFOLR1/hCD47 subcutaneously at 1×106 cells /mouse inoculum for tumor development.

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Fig3. hFOLR1 and hCD47 expression in tumors after in vivo growth of MC38-hFOLR1/hCD47 in wild type C57BL/6 mice. The tumors were collected at day 25 post tumor cell inoculation.

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Fig4. hFOLR1 and hCD47 expression in tumors after in vivo growth of MC38-hFOLR1/hCD47 in wild type C57BL/6 mice. The tumors were collected at day 35 post tumor cell inoculation.

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