MC38-hTROP2

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Strain Information

Cell Line

MC38-Igs2em1(hTROP2)Smoc

Cat. NO.

NM-S13-TM61

Model Description

A Trop2 expression cassette was knocked into the H11 locus.

Strain State

Validation of tumorigenic capacity completed

Validation Data

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Fig1. hTROP2 expression on in vitro cultured cells of MC38-hTROP2.

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Fig2. In vivo validation of MC38-hTROP2 in C57BL/6 mice.

C57BL/6 mice were inoculated with MC38-hTROP2 subcutaneously at 1×106 cells/mouse inoculum for tumor development.

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Fig3. hTROP2 expression in tumors after in vivo growth of MC38-hTROP2 in wild type C57BL/6 mice.

The tumors were collected at day 28 post tumor cell inoculation.

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