hEBI3

Nomenclature

C57BL/6Smoc-Ebi3tm1(hEBI3)Smoc

Cat. NO.

NM-HU-234509

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ebi3

Model Description

The endogenous mouse Ebi3 gene was replaced by human EBI3 gene.

Validation Data

image.png

Fig.1 Detection of EBI3 expression in spleen by RT-PCR. 

Wild type: only one band at 138 bp with primers F1/R1(mEbi3); 

Homozygous: only one band at 117 bp with primers F2/R2(hEBI3). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hEBI3 expression in serum by ELISA. 

Abbr. HO, homozygous; WT, wild type. 

Note. hEBI3 and C57BL/6 mice were i.p. injected with LPS. The human EBI3 ELISA kit cross- reacted with mEBI3 and humanized EBI3.


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