hRTN4R

Nomenclature

C57BL/6Smoc-Rtn4rem1(hRTN4R)Smoc

Cat. NO.

NM-HU-234373

Strain State

Repository Live

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Gene Summary

Gene Symbol
Rtn4r

Model Description

The endogenous mouse Rtn4r gene was replaced by human RTN4R gene.

Validation Data

image.png

Fig.1 Detection of RTN4R expression in frontal lobe and cerebellum by RT-PCR. 

Wild type: only one band at 421 bp with primers F1/R1(mRtn4r);

Homozygous: only one band at 190 bp with primers F2/R2(hRTN4R).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human RTN4R expression in hRTN4R knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, HepG2 cells.

Note. The anti-human RTN4R antibody cross-reacted with mouse RTN4R and humanized RTN4R. 

image.png

Fig.3 Detection of human RTN4R expression in hRTN4R knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, HepG2 cells.

Note. The anti-human RTN4R antibody cross-reacted with mouse RTN4R and humanized RTN4R. 


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