hCXCR4

Nomenclature

C57BL/6Smoc-Cxcr4tm1(hCXCR4)/Smoc

Cat. NO.

NM-HU-2000081

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cxcr4

Synonyms

CD184; LESTR; Sdf1r; CXC-R4; CXCR-4; Cmkar4; PB-CKR; b2b220Clo; PBSF/SDF-1

Chromosome

1

NCBI ID

12767

MGI ID

109563

Ensembl ID

ENSMUSG00000045382

Pubmed

Cxcr4

Human Ortholog

CXCR4

Model Description

The endogenous mouse Cxcr4 gene was replaced by human CXCR4 gene.
Research Application：Immunotherapy,drug screening

Validation Data

image.png

Fig.1 Detection of CXCR4 expression in thymus by RT-PCR. (male, 13 weeks old) 

Wild type: only one band at 248 bp with primers F1/R1(mCxcr4);

Homozygous: only one band at 319 bp with primers F2/R2(hCXCR4).Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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