Cd8a-IRES-DTRGFP

Nomenclature

C57BL/6Smoc-Cd8aem2(IRES-DTREGFP)Smoc

Cat. NO.

NM-KI-190045

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cd8a

Synonyms

Ly-2; Ly-B; Ly-35; Lyt-2; BB154331

NCBI ID

12525

MGI ID

88346

Ensembl ID

ENSMUSG00000053977

Pubmed

Cd8a

Human Ortholog

CD8A

Model Description

A IRES-DTREGFP expression cassette was knocked into the Cd8a gene stop codon site.

Validation Data

image.png

Fig.1 Expression analysis of CD8 and GFP on CD3+T in blood of CD8a-IRES-DTRGFP mice.

Leukocytes were collected from the blood of 9-week-old CD8a-IRES-DTRGFP mice, and analyzed by flow cytometry. Most CD8+T cells (94.4%) were GFP-positive cells.

Publications 1piece

1. Different syngeneic tumors show distinctive intrinsic tumor-immunity and mechanisms of actions (MOA) of anti-PD-1 treatment
Published year：2022 References：Scientific reports

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