Apoe-KO/Nos3-KO

Nomenclature

C57BL/6Smoc-Apoeem5Nos3em1Smoc

Cat. NO.

NM-XA-242509

Strain State

Repository Live

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Gene Summary

Gene Symbol
Apoe

Synonyms

Apo-E; AI255918

Chromosome

7

NCBI ID

11816

MGI ID

88057

Ensembl ID

ENSMUSG00000002985

Pubmed

Apoe

Human Ortholog

APOE

Model Description

The Apoe-KO(2)(NM-KO-190565) was crossed with Nos3-KO(NM-KO-18022) to generate Apoe-KO/Nos3-KO mice.

Validation Data

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Fig.1 Detection of Apoe/Nos3 expression in mammary gland by RT-PCR. 

Wild type: one band at 987 bp with primers F1/R1(mApoe), one band at 113 bp with primers F2/R2(mNos3) and one band at 123 bp with primers F/R(mGapdh).

Homozygous: one band at ~150bp with primers F1/R1(mApoe) and one band at 123 bp with primers F/R(mGapdh).

Heterozygous: two bands at 987 bp/~150bp with primers F1/R1(mApoe) and one band at 123 bp with primers F/R(mGapdh).

Abbr. M, DNA marker; HE, heterozygous; HO, homozygous; WT, wild type.

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