Hdc-2A-CreERT2
Nomenclature
C57BL/6Smoc-Hdcem(2A-CreERT2)Smoc
Cat. NO.
NM-KI-220044
Strain State
Sperm cryopreservation
Gene Summary
Gene Symbol
Hdc
Model Description
Validation Data
Fig1. CreERT2 mediated recombination in brain of HdcCreERT2/+; Rosa26tdTomato/+ mouse.
Fig2. Detection of tdTomato(red) in various tissues of HdcCreERT2/+; Rosa26tdTomato/+ mouse.
The tissues that express tdTomato include: brain, spinal cord, lungs, liver, stomach, adrenal glands, kidneys, spleen, reproductive organs, thymus, and pituitary gland. Tissues with minimal tdTomato expression include: small intestine and skin.
Tissues that do not express tdTomato: heart, eyes, salivary glands, brown adipose tissue, pancreas, large intestine, and muscle.
In the control group, tdTomato shows very minimal leaky expression in the brain, stomach, adrenal glands, kidneys, spleen, and thymus. (8-weeks old, male) (For more detailed information please contact our technical advisor.)
Publications
An H2R-dependent medial septum histaminergic circuit mediates feeding behavior
References：Current Biology
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