hCCL5

Nomenclature

C57BL/6Smoc-CCL5tm1(hCCL5)/Smoc

Cat. NO.

NM-HU-210014

Strain State

不对外出售

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Gene Summary

Gene Symbol
Ccl5

Synonyms

SISd; Scya5; RANTES; TCP228; MuRantes

NCBI ID

20304

MGI ID

98262

Ensembl ID

ENSMUSG00000035042

Pubmed

Ccl5

Human Ortholog

CCL5

Model Description

The endogenous mice Ccl5 gene was replaced by human CCL5 gene.
Research Application：drug screening

Validation Data

image.png

Fig1. Detection of CCL5 expression in small intestine by RT-PCR. 

Wild type: only one band at 242 bp with primers F1/R1(mCcl5);

Heterozygous: one band at 242 bp with primers F1/R1(mCcl5) and one band at 217 bp with primers F2/R2(hCCL5); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hCCL5 and mCCL5 expression in serum by ELISA (n=2). 

Abbr. HE, heterozygous; WT, wild type.

Note. hCCL5 and C57BL/6 mice were i.p. injected with LPS for 3h.

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