SMOC has developed a set of mouse models expressing humanized cytokines receptors. These models are suitable to assess the efficacy of drugs targeting cytokines receptors in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Tnfrsf8tm(hTNFRSF8)Smoc
Strain State：Developing | Cat. NO.：NM-HU-220202
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Strain Name：C57BL/6Smoc-Itgamem1(IRES-hCD89-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200063
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hCD2 C truncated-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200321
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Kozak-hEGFRvIII-IRES-Luc-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-233898
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-FCGR2A-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200229
Research Application：Fluorescence Tracer Mice
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200255
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR2(K659N)-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190078
Research Application：cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR2(S320C)-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190079
Research Application：cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190080
Research Application：cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190007
Research Application：cancer
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