In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6JSmo-Igf1rtm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200187
Research Application：Study on the relationship between G protein signal transduction and RhoA regulatory pathway and oocyte meiosis
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Strain Name：C57BL/6JSmo-Igf1rem(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220208
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Strain Name：C57BL/6JSmo-Igf2bp2em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200101
Research Application：Related research on gene expression and MAPK-Erk pathway
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Strain Name：C57BL/6JSmo-Igf2bp3em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2110528
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Strain Name：C57BL/6JSmo-Igf2rem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-251673
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Strain Name：C57BL/6JSmo-Igfbp1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-232312
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Strain Name：C57BL/6JSmo-Igfbp2em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-240328
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