Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Fesem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240050
Mice
Strain Name:C57BL/6Smoc-Fetubem1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-252980
Mice
Strain Name:C57BL/6Smoc-Fevem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240047
Mice
Strain Name:C57BL/6Smoc-Fez1em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-260885
Mice
Strain Name:C57BL/6Smoc-Fez2em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-260838
Mice
Strain Name:C57BL/6Smoc-Fezf1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Fezf2em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ffar1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2112449
Mice
Strain Name:C57BL/6Smoc-Ffar2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200246
Mice
Strain Name:C57BL/6Smoc-Ffar3em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2109785
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