In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6Smoc-Fcer2aem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234056
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Strain Name：C57BL/6Smoc-Fcf1em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253631
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Strain Name：C57BL/6Smoc-Fcgbpem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-260876
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Strain Name：C57BL/6Smoc-Fcgr1em(flox)/Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-220625
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Strain Name：C57BL/6Smoc-Fcgr2bem(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220582
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Strain Name：C57BL/6Smoc-Fcgrtem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200094
Research Application：Antigen binding and β-2-microglobulin binding related research
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Strain Name：C57BL/6Smoc-Fcho1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253688
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