Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Fbll1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Fbln1em(flox)/Smoc
Strain State:Developing | Cat. NO.:NM-CKO-230504
Mice
Strain Name:C57BL/6Smoc-Fbln2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2104542
Mice
Strain Name:C57BL/6Smoc-Fbln5em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-260875
Mice
Strain Name:B6;129S-Fbln7tm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-00120
Mice
Strain Name:C57BL/6Smoc-Fbn1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200325
Mice
Strain Name:C57BL/6Smoc-Fbn1em2(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-215082
Mice
Strain Name:C57BL/6Smoc-Fbn1tm1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226504
Mice
Strain Name:C57BL/6Smoc-Fbn2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-205169
Mice
Strain Name:C57BL/6Smoc-Fbp1em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-260764
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