In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6Smoc-Elf1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-242035
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Strain Name：C57BL/6Smoc-Elf2tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-250104
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Strain Name：C57BL/6Smoc-Elf3em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-252659
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Strain Name：C57BL/6Smoc-Elk3tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-232271
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Strain Name：C57BL/6Smoc-Elk4em1(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-230446
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Strain Name：C57BL/6Smoc-Ellem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-240997
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