Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-D14Ertd670eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D16Ertd472eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D17H6S53Eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D1Ertd622eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D1Pas1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D2hgdhem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D3Ertd751eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D5Ertd577eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D5Ertd605eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-D5Ertd615eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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