In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6Smoc-Cyp17a1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-241069
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Strain Name：C57BL/6Smoc-Cyp19a1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-210026
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Strain Name：C57BL/6Smoc-Cyp1a1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253949
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Strain Name：C57BL/6Smoc-Cyp1a2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-251688
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Strain Name：C57BL/6Smoc-Cyp1b1tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-240158
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Strain Name：C57BL/6Smoc-Cyp24a1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-240998
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Strain Name：C57BL/6Smoc-Cyp26a1em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220219
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Strain Name：C57BL/6Smoc-Cyp26a1em1(flox)Cyp26c1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-240007
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