Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Zzef1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-1110038F14Rikem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226005
Mice
Strain Name:C57BL/6Smoc-1700007K13Rikem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-2210010C04Rikem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-3830417A13Rikem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226191
Mice
Strain Name:C57BL/6Smoc-4930469K13Rikem1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-232130
Mice
Strain Name:C57BL/6Smoc-4932438A13Rikem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-225005
Mice
Strain Name:C57BL/6Smoc-5430431A17Rikem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-9930012K11Rikem1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-205218
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