In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Mice
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Mice
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Strain Name:C57BL/6Smoc-Usp46em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-260686
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Mice
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Strain Name:C57BL/6Smoc-Usp47em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-250170
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Mice
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Strain Name:C57BL/6Smoc-Usp48em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2117105
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Mice
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Strain Name:C57BL/6Smoc-Usp5em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2102616
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Mice
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Mice
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Strain Name:C57BL/6Smoc-Usp51em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226371
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Mice
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Strain Name:C57BL/6Smoc-Usp53em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2104492
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Mice
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Strain Name:C57BL/6Smoc-Usp54em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-253827
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Mice
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Strain Name:C57BL/6Smoc-Usp6nlem1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-205100
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