Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

mouse
Strain Name:C57BL/6Smoc-Rbm27em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Rbm28em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-241864
mouse
Strain Name:C57BL/6JSmo-Rbm3em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-250793
mouse
Strain Name:C57BL/6Smoc-Rbm31yem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Rbm33em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-242025
mouse
Strain Name:C57BL/6JSmo-Rbm34em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-241861
mouse
Strain Name:C57BL/6Smoc-Rbm38em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6Smoc-Rbm3osem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6Smoc-Rbm41em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Rbm42em(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-220043
Email Back to top