Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

mouse
Strain Name:C57BL/6Smoc-Prdm14em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Prdm15em1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-210050
mouse
Strain Name:C57BL/6JSmo-Prdm16em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200208
Research Application:Research on Respiratory Electronic Transport
mouse
Strain Name:C57BL/6JSmo-Prdm2tm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-190034
Research Application:Epigenetic
mouse
Strain Name:C57BL/6JSmo-Prdm4em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-242306
mouse
Strain Name:C57BL/6JSmo-Prdm5em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-254101
mouse
Strain Name:C57BL/6JSmo-Prdm6em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226385
mouse
Strain Name:C57BL/6Smoc-Prdm9em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Prdx1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2102481
mouse
Strain Name:C57BL/6JSmo-Prdx2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2112418
Email Back to top