In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6JSmo-Plgem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253008
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Strain Name：C57BL/6JSmo-Plgrktem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253699
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Strain Name：C57BL/6JSmo-Plin2em(flox)/Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-230490
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Strain Name：C57BL/6JSmo-Plin4em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-241279
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Strain Name：C57BL/6JSmo-Plin5em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-251975
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Strain Name：C57BL/6JSmo-Plk1tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2100165
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Strain Name：C57BL/6JSmo-Plk2em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-226410
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