Lep-KO
Nomenclature
B6;129S-Leptm1Smoc
Cat. NO.
NM-KO-00034
Strain State
Repository Live
Gene Summary
Gene Symbol
Lep
Model Description
Validation Data
Fig1. Body weight and Blood glucose monitoring of ob/ob mice.
Fig2. Evaluation of Oral glucose tolerance test (OGTT) of female ob/ob mice.
Abbr. HO, homozygous; WT, wild type. **, P ≤ 0.01.
Note. The tested ob/ob and C57BL/6 mice were 6 weeks old.
Fig3. Detection of insulin levels in serum by ELISA.
Abbr. Hom, homozygous; HE, heterozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old.
Fig4. H&E staining of the subcutaneous adipose tissue (SAT) in ob/ob mice.
Abbr. HO, homozygous; WT, wild type; WAT, white adipose tissue; BAT, brown adipose tissue.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 20.
Fig5. Representative pictures of pancreas in ob/ob mice.
These results suggested the inflammatory cell infiltration of the pancreas in ob/ob mice.
Abbr. HO, homozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 10.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreAt GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
