BALB/c Nude

Nomenclature

BALB/cAnSmoc-Foxn1nu/Smoc

Cat. NO.

SM-014

Strain State

Repository Live

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Model Description

BALB/c背景下Foxn1基因纯合突变，裸鼠是快速生长的肿瘤细胞系的理想宿主，但部分细胞系在裸鼠上难以成瘤，如血液瘤细胞系、乳腺癌细胞系、原代细胞等。裸鼠无毛，更容易直观的评估皮下肿瘤的生长情况。

Validation Data

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Fig1. Body weight growth curve of BALB/c Nude (n=780)

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Fig2. Complete deletion of T, B cells of BALB/c Nude. 

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Fig3. Subcutaneous xenograft tumor growth in BALB/c Nude. 

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Fig4. Blood routine tests in BALB/c Nude.

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Fig5. Blood biochemistry in BALB/c Nude.

Table 1. BALB/c Nude xenograft cell lines

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Publications 26piece

1. Targeting the FOSL1/IKKα positive feedback loop attenuates glioblastoma malignancy via suppression of NF-κB signaling
Published year：2026 References：Theranostics

2. Loss of TFAM Accelerates Pentose Phosphate Pathway by Unleashing G6PD Oligomerization to Drive Hepatocarcinogenesis
Published year：2026 References：CANCER LETTERS

3. MD2 suppresses anaplastic thyroid Cancer progression by reprogramming macrophages via USP15-mediated FHL1 Deubiquitination
Published year：2026 References：INTERNATIONAL IMMUNOPHARMACOLOGY

4. FOXA2/ALDOB axis modulation of fatty acid beta-oxidation influences irinotecan resistance in colorectal cancer
Published year：2026 References：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

5. Multi-omics analysis identifies BUB1B as a cell cycle–related driver of bladder cancer progression
Published year：2026 References：World Journal of Surgical Oncology

6. RNA target-independent non-canonical activation (RINCA) of Cas13 trans-nuclease activity
Published year：2025 References：Science Bulletin

7. Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells
Published year：2025 References：Cell Death & Disease

8. Sino-C, a novel sinomenine derivative, induces cell death by disrupting cholesterol homeostasis in colorectal cancer cells
Published year：2025 References：ACTA PHARMACOLOGICA SINICA

9. The lysosomal cysteine protease cathepsin L promotes stemness and multidrug resistance of non-small cell lung cancer by targeting HGF activator
Published year：2025 References：MOLECULAR AND CELLULAR BIOCHEMISTRY

10. Unraveling the secrets of UBE2S in endometrial cancer: Potential targets for diagnosis, prognostic assessment, and ferroptosis therapy
Published year：2025 References：CELLULAR SIGNALLING

11. APOBEC3B-driven mutations negatively regulated by P53 promote tumor progression and immunosuppressive microenvironment in prostate cancer
Published year：2025 References：MOLECULAR AND CELLULAR BIOCHEMISTRY

12. BRAP Promotes the Tumorigenesis of Hepatocellular Carcinoma by Corrupting Cancer Cell Cycle Regulation and Enhancing Immune Evasion
Published year：2025 References：Journal of Hepatocellular Carcinoma

13. VDAC1 as prognostic marker and therapeutic target in lung adenocarcinoma: a study integrating bioinformatics and experimental validation
Published year：2025 References：Discover Oncology

14. Acevaltrate as a novel ferroptosis inducer with dual targets of PCBP1/2 and GPX4 in colorectal cancer
Published year：2025 References：Signal Transduction and Targeted Therapy

15. BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
Published year：2024 References：Cell Host & Microbe

16. Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation
Published year：2024 References：DRUG RESISTANCE UPDATES

17. Effect of Bioactive Black Phosphorus Nanomaterials on Cancer-Associated Fibroblast Heterogeneity in Pancreatic Cancer
Published year：2024 References：ACS Nano

18. Aspirin-Mediated Acetylation of SIRT1 Maintains Intestinal Immune Homeostasis
Published year：2024 References：Advanced Science

19. Dual Inhibition of CDK4/6 and CDK7 Suppresses Triple-Negative Breast Cancer Progression via Epigenetic Modulation of SREBP1-Regulated Cholesterol Metabolism
Published year：2024 References：Advanced Science

20. A STT3A-dependent PD-L1 glycosylation modification mediated by GMPS drives tumor immune evasion in hepatocellular carcinoma
Published year：2024 References：CELL DEATH AND DIFFERENTIATION

21. Cuproptosis and Serine Metabolism Blockade Triggered by Copper-Based Prussian Blue Nanomedicine for Enhanced Tumor Therapy
Published year：2024 References：Small

22. Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
Published year：2023 References：Molecular Cancer

23. Targeted therapy of central nervous system acute lymphoblastic leukemia with an integrin α6-targeted self-assembling proapoptotic nanopeptide
Published year：2023 References：Engineering

24. Epitranscriptic regulation of HRAS by N6-methyladenosine drives tumor progression
Published year：2023 References：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

25. Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1
Published year：2022 References：Nature Communications

26. RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA
Published year：2021 References：Clinical and Translational Medicine

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