hCD19(BALB/c)

Nomenclature

BALB/cAnSmoc-Cd19em1(hCD19)Smoc

Cat. NO.

NM-HU-220606

Strain State

Repository Live

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Gene Summary

Gene Symbol
CD19

Synonyms

AW495831

NCBI ID

12478

MGI ID

88319

Ensembl ID

ENSMUSG00000030724

Pubmed

CD19

Human Ortholog

CD19

Model Description

The endogenous mouse Cd19 gene was replaced by human CD19 gene.

Validation Data

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Fig1. Detection of hCD19 expression on B cells in Blood in hCD19 KI mice.

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Table 1. Blood routine examination of hCD19(BALB/c) knockin mice. 

Abbr. HO, homozygous.

Values are expressed as mean±SEM.

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Fig.2 Body weight and ratios of spleen, thymus and MLN to body weight of 8-week-old hCD19(BALB/c) knokcin mice. (n=7 for female WT group and n=6 for each other group, Mean±SEM, Unpaired t-test, **P<0.01,  ****P<0.0001).

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Table 2. Biochemical test of serum from hCD19(BALB/c) knockin mice. 

Abbr. HO, homozygous; WT, wild type.

Values are expressed as mean±SEM.

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Fig.3 Blood biochemical test of 8-week-old hCD19 (BALB/c) knokcin mice. (n=6 for all groups, Mean±SEM, Unpaired t-test, *p<0.05).

Abbr. HO, homozygous; WT, wild type.

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Fig.4 Detection of myeloid cell subsets in the blood of hCD19(BALB/c) knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

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Fig.5 Detection of lymphocyte subsets in the blood of hCD19(BALB/c) knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

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Fig.6 Detection of myeloid cell subsets in the spleen of hCD19(BALB/c) knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

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Fig.7 Detection of lymphocyte subsets in the spleen of hCD19(BALB/c) knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

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