hCCR7

Nomenclature

C57BL/6Smoc-Ccr7tm(hCCR7)Smoc

Cat. NO.

NM-HU-220284

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ccr7

Model Description

The endogenous mouse Ccr7 gene was replaced by human CCR7 gene.

Validation Data

image.png

Fig.1 Detection of CCR7 expression in spleen by RT-PCR. 

Wild type: only one band at 221 bp with primers F1/R1(mCcr7);

Homozygous: only one band at 396 bp with primers F2/R2(hCCR7).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hCCR7 expressed on T cells in Peripheral Blood and Spleen in HO hCCR7 KI mice.


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