hCD3EDG/hPSMA

Nomenclature

C57BL/6Smoc-Cd3etm(hCD3E)Cd3dtm(hCD3D)Cd3gtm(hCD3G)Folh1tm(hFOLH1B)Smoc

Cat. NO.

NM-HU-220251

Strain State

Embryo cryopreservation

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Model Description

hPSMA (NM-HU-200240) was crossed with hCD3EDG (NM-HU-220120) to generate hPD-1/hTIGIT.

Validation Data

image.png

Fig1. Detection of PSMA expression in kidney by RT-PCR. 

Wild type: only one band at 294 bp with primers F1/R1(mPsma); Heterozygous: one band at 294 bp with primers F1/R1(mPsma) and  one band at 169 bp with primers F2/R2(hPSMA);  Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of human PSMA expression in Prostate by IHC.

Note. The human PSMA antibody cross-reacted with mouse PSMA and human PSMA.

Abbr. HO, homozygous; WT, wild type.



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