pAtp4b-hCLDN18.2-Tg

Nomenclature

C57BL/6Smoc-Tg(pAtp4b-hCLDN18.2)1Smoc

Cat. NO.

NM-TG-220197

Strain State

Repository Live

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Model Description

These transgenic mice harbor pAtp4b-hCLDN18.2 expression cassettes.

Validation Data

image.png

Fig.1  Detection of CLDN18.2 expression in stomach and lung of pAtp4b-hCLDN18.2-Tg (+) mice by RT-PCR. 

Wild type: one band at 140 bp with primers F1/R1(mAtp4b) and one band at 123 bp with primers F/R(mGapdh);

pAtp4b-hCLDN18.2-Tg (+): one band at 140 bp with primers F1/R1(mAtp4b); one band at 212 bp with primers F2/R2(hCLDN18.2) and one band at 123 bp with primers F/R(mGapdh). 

Abbr. M, DNA marker; WT, wild type.

image.png

Fig.2  Detection of human CLDN18.2 expression in stomach by FACS. 

Abbr.  WT, wild type.

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