hIL11/hIL11RA
Nomenclature
C57BL/6Smoc-Il11em1(hIL11)Il11ra1tm1(hIL11RA)/Smoc
Cat. NO.
NM-HU-210372
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Tnfrsf4
Gene Symbol
Il11ra1
Model Description
Validation Data
Fig.1 Detection of IL11 expression in testis,stomach and lung by RT-PCR in hIL11/hIL11RA dKI mice.
Wild type: only one band at 171 bp with primers F1/R1(mIl11);
Homozygous: only one band at 162 bp with primers F2/R2(hIL11).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of IL11RA expression in testis, stomach and lung by RT-PCR in hIL11/hIL11RA dKI mice.
Wild type: only one band at 289 bp with primers F1/R1(mIl11ra);
Homozygous: only one band at 247 bp with primers F2/R2(hIL11RA).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.3 Detection of hIL11 expression in lung homogenate by ELISA in hIL11/hIL11RA dKI mice.
Abbr. HO, homozygous; WT, wild type.
Note. hIL11/hIL11RA and C57BL/6 mice were injected with LPS.
Fig.4 Detection of human IL11RA expression in hIL11/hIL11RA dKI mice by WB.
Abbr. HO, homozygous; WT, wild type.
Note. The IL11RA Antibody cross-reacted with mouse and humanized IL11RA.
Fig.5 Detection of hIL11RA expression in Kidney in C57BL/6 and HO/HO hIL11/hIL11RA knockin mice by IHC.
Abbr. HO/HO, homozygous; WT, wild type.
Note. The IL11RA Antibody cross-reacted with mouse and humanized IL11RA.
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