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Models

About 43,982 results
Mice

hCD44

Strain Name：C57BL/6Smoc-Cd44em(hCD44)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215003
Validation Data：Presence

The endogenous mice Cd44 gene was replaced by human CD44 gene.

Mice

Adcy5-KO

Strain Name：C57BL/6Smoc-Adcy5em1Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

Exon 3 of Adcy5 gene was deleted to generate Adcy5 knockout mice.

Mice

hCD3E/hCD28

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E))Cd28em2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210233
Validation Data：Absence

hCD3E(NM-HU-00114) was crossed with hCD28(NM-HU-190011) to generate hCD3E/hCD28 mice.

Mice

hIL7

Strain Name：C57BL/6Smoc-Il7em1(hIL7)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190031
Validation Data：Presence

The endogenous mouse Il7 gene was replaced by human IL7 gene.

Mice

hIDO1

Strain Name：B6;129S-Ido1em1(hIDO1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00061
Validation Data：Presence

The endogenous mouse Ido1 gene was replaced by human IDO1 gene.

Mice

Fah-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Fahem2Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-004
Validation Data：Absence

Exon 3 of Fah gene was deleted to generate Fah knockout mice.

Mice

hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106
Validation Data：Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

hCD74

Strain Name：C57BL/6Smoc-Cd74em1(hCD74)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000082
Validation Data：Absence

The endogenous mouse Cd74 gene was replaced by human CD74 gene.

Mice

Nkx2-1-CreERT2

Strain Name：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200123
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

Mice

hSIGLEC15

Strain Name：C57BL/6Smoc-Siglec15em1(hSIGLEC15)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190037
Validation Data：Presence

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene.

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