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Models

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Mice

hTLR4

Strain Name：C57BL/6Smoc-Tlr4tm2(hTLR4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000025
Validation Data：Presence

The endogenous mouse Tlr4 gene was replaced by human TLR4 gene.

Mice

hCD3E/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E))Cd38tm2(hCD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210234

hCD3E(NM-HU-00114) was crossed with hCD38(2)(NM-HU-190059) to generate hCD3E/hCD38(2) mice.

Mice

hIL2RG

Strain Name：C57BL/6Smoc-Il2rgtm1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200007

The endogenous mouse Il2rg gene was replaced by human IL2RG gene.

Mice

Cd2-2A-CreERT2

Strain Name：C57BL/6Smoc-Cd2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18017
Validation Data：Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Map2-2A-CreERT2

Strain Name：C57BL/6Smoc-Map2em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00037
Validation Data：Presence  |  Publications：1piece

Map2 is a marker of mature neurons. A 2A-CreERT2 cassette was inserted before the translational termination site of the Map2 locus.

Mice

hCD73(2)

Strain Name：C57BL/6Smoc-Nt5etm3(NT5E)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200009
Validation Data：Presence

The endogenous mouse Nt5e gene was replaced by human NT5E gene.

Mice

hIL21

Strain Name：C57BL/6Smoc-Il21tm1(hIL21)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200255
Validation Data：Presence

The endogenous mice Il21 gene was replaced by human IL21 gene.

Mice

hCXCR6

Strain Name：C57BL/6Smoc-Cxcr6tm(hCXCR6)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215001
Validation Data：Presence

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

Mice

hPD-L1/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Tnfrsf9tm2(h4-1BB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200260

hPD-L1(NM-HU-00062) was crossed with h4-1BB(2)(NM-HU-190077) to generate hPD-L1/h4-1BB(2).

Mice

hSIGLEC8

Strain Name：C57BL/6Smoc-Siglecetm1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983

The endogenous mice Siglece gene was replaced by human SIGLEC8 gene. While hSIGLEC8(2)(Stock No.NM-HU-210033) mice function similarly to hSIGLEC8 mice,for more detailed information please contact our technical advisor.

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