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Models

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Mice

Shh-CreERT2

Strain Name：C57BL/6Smoc-Shhem1(CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200145
Validation Data：Presence

A CreERT2-WPRE-polyA expression cassette was knocked into the Shh gene start codon site.

Mice

hCD3EDG(BALB/c)

Strain Name：BALB/c-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Strain State：Repository Live | Cat. NO.：NM-HU-220122
Validation Data：Presence

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

Mice

hPD-1/hPD-L1(2)/hCCR8

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-210402
Validation Data：Absence

hPD-1(NM-HU-00015) and hPD-1(2)(NM-HU-190039) were crossed with hCCR8(NM-HU-190053) to generate hPD-1/hPD-L1(2)/hCCR8 mice.

Mice

hSORT1

Strain Name：C57BL/6Smoc-Sort1em1(hSORT1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225035
Validation Data：Presence

The endogenous mouse Sort1 gene was replaced by human SORT1 gene.

Mice

hPSGL-1

Strain Name：C57BL/6Smoc-Selplgem1(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00046
Validation Data：Presence

The endogenous mouse Selplg gene was replaced by human SELPLG gene.

Mice

Ins2-C96Y

Strain Name：C57BL/6Smoc-Ins2em3(C96Y)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190096
Validation Data：Presence

These mice carry a p.C96Y mutation of Ins2 gene.

Mice

hSDC1

Strain Name：C57BL/6Smoc-Sdc1em1(hSDC1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000026
Validation Data：Presence

The endogenous mouse Sdc1 gene was replaced by human SDC1 gene.

Mice

Nphs2-CreERT2

Strain Name：C57BL/6Smoc-Nphs2tm1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00128
Validation Data：Presence

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Nphs2 gene via homologous recombination to establish a tamoxifen inducible Nphs2-CreERT2 tool stain.

Mice

hIL11/hIL11RA

Strain Name：C57BL/6Smoc-Il11em1(hIL11)Il11ra1em1(hIL11RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210372
Validation Data：Presence

hIL11(NM-HU-204981) was crossed with hIL11RA (NM-HU-204982) to generate hIL11/hIL11RA mice.

Mice

hCRLF2

Strain Name：C57BL/6Smoc-Crlf2em1(hCRLF2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210028
Validation Data：Absence

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.

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