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Models

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Mice

hCD3EDG/hCD19

Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd19tm1(hCD19)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220109
Validation Data：Presence

hCD3EDG(NM-HU-220120) mice were crossed with hCD19(NM-HU-00110) mice to generate hCD3EDG/hCD19 mice.

Mice

hIL31

Strain Name：C57BL/6JSmo-Il31tm2(IL31)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200008
Validation Data：Presence

The endogenous mouse Il31 gene was replaced by human IL31 gene.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1

Strain Name：C57BL/6JSmo-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220068

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1(NM-HU-00015) mouse.

Mice

hIL2RA/hIL2RB/hIL2RG

Strain Name：C57BL/6JSmo-Il2ratm1(hIL2RA)Il2rgtm1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210414
Validation Data：Presence

hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.

Mice

hCTLA-4/h4-1BB(2)

Strain Name：C57BL/6JSmo-Ctla4tm1(hCTLA4)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210355

hCTLA4(NM-HU-00014) was crossed with h4-1BB(2)(NM-HU-190077）to generate hCTLA4/h4-1BB(2) mice.

Mice

Col1a1-IRES-CreERT2

Strain Name：C57BL/6JSmo-Col1a1em(IRES-CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225031
Validation Data：Presence

IRES-CreERT2 expression cassette was knocked into the Col1a1 gene. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Wnt1-Dre

Strain Name：C57BL/6JSmo-Wnt1em1(Dre-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200176
Validation Data：Presence

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

Mice

hNCR3

Strain Name：C57BL/6JSmo-Ncr1tm1(hNCR3)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215066
Validation Data：Presence

The endogenous mouse Ncr1 gene was replaced by human NCR3 gene.

Mice

hCXCR3

Strain Name：C57BL/6JSmo-Cxcr3tm1(hCXCR3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200219
Validation Data：Presence

The endogenous mouse Cxcr3 gene was completely or partially replaced by human CXCR3 gene via ESC targeting.

Mice

hIL18BP

Strain Name：C57BL/6JSmo-Il18bptm1(hIL18BP)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210039
Validation Data：Presence

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

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