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Models

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Mice

hGNRHR

Strain Name：C57BL/6Smoc-Gnrhrem(hGNRHR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220137
Validation Data：Presence

The endogenous mouse Gnrhr gene was replaced by human GNRHR gene.

Mice

Foxp3-IRES-tdTomato-2A-CreERT2

Strain Name：C57BL/6Smoc-Foxp3em4(IRES-tdTomato-2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190120
Validation Data：Presence

A IRES-tdTomato-2A-CreERT2 expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

hCD3EDG

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220120
Validation Data：Presence

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

Mice

hFCGR2B/h4-1BB(2)

Strain Name：C57BL/6Smoc-Fcgr2bem2(FCGR2B)Tnfrsf9em2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210352
Validation Data：Presence

hFCGR2B(NM-HU-2000010) was crossed with h4-1BB (NM-HU-190077) to generate hFCGR2B/h4-1BB mice.

Mice

hTLR4

Strain Name：C57BL/6Smoc-Tlr4em2(hTLR4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000025
Validation Data：Presence

The endogenous mouse Tlr4 gene was replaced by human TLR4 gene.

Mice

Txlna-Luc-EGFP

Strain Name：C57BL/6Smoc-Txlnaem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00026
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Txlna.

Mice

hPTPN1

Strain Name：C57BL/6Smoc-Ptpn1em1(hPTPN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225059
Validation Data：Presence

The endogenous mouse Ptpn1 gene was replaced by human PTPN1 gene.

Mice

Zap70-W163C(Balb/c)

Strain Name：BALB/cAnSmoc-Zap70em(W163C)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210366
Validation Data：Presence

These mice carry a W163C mutation of Zap70 gene.

Mice

Slc17a6-CreERT2

Strain Name：C57BL/6Smoc-Slc17a6em2(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190011
Validation Data：Presence

This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.

Mice

hCYP2D

Strain Name：C57BL/6Smoc-Cyp2dem(hCYP2D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215016
Validation Data：Absence

The endogenous mouse Cyp2d gene was replaced by human CYP2D gene.

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