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Models

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Mice

Bhlha15-CreERT2(2)

Strain Name：C57BL/6Smoc-Bhlha15em2(kozak-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200158

A kozak-CreERT2-WPRE-polyA expression cassette was knocked into the Bhlha15 gene start codon site. While Bhlha15-CreERT2 (Stock No. NM-KI-200080) mice were generated through replacing the coding region of Bhlha15 gene with a CreERT2 expression cassette.

Mice

R26-CAG-LSL-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190095
Validation Data：Presence  |  Publications：1piece

A CAG-LSL-Luciferase-2A-EGFP-wpre-polyA expression cassette was inserted at the Rosa26 locus site.

Mice

Isl1-Cre

Strain Name：C57BL/6Smoc-Isl1em1(iCre-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200126
Validation Data：Presence

A iCre-WPRE-pA expression cassette was knocked into the Isl1 gene start codon site.

Mice

hCYP2D

Strain Name：C57BL/6Smoc-Cyp2dtm(hCYP2D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215016

The endogenous mouse Cyp2d gene was replaced by human CYP2D gene.

Mice

hCXCR3

Strain Name：C57BL/6Smoc-Cxcr3tm1(hCXCR3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200219
Validation Data：Presence

The endogenous mouse Cxcr3 gene was completely or partially replaced by human CXCR3 gene via ESC targeting.

Mice

C1qa-KO

Strain Name：C57BL/6Smoc-C1qaemSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210110

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

Mice

hIl5

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001
Validation Data：Presence

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Mice

Trp63-CreERT2

Strain Name：C57BL/6Smoc-Trp63em(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225021
Validation Data：Presence

A CreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene via CRISPR/Cas mediated recombination.

Mice

Krt5-2A-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190016
Publications：1piece

The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.

Mice

Sox10-2A-Cre

Strain Name：C57BL/6Smoc-Sox10em(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220066
Validation Data：Presence

2A-Cre expression cassette was knocked into the Sox10 gene stop codon site. The target gene is associated with pigment, and heterozygotes are recommended for mating in breeding.

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