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Models

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Mice

hCLDN6

Strain Name：C57BL/6Smoc-Cldn6tm1(hCLDN6)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225034
Validation Data：Presence

The endogenous mouse Cldn6 gene was replaced by human CLDN6 gene.

Mice

hSDC1

Strain Name：C57BL/6Smoc-Sdc1tm1(hSDC1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000026
Validation Data：Presence

The endogenous mouse Sdc1 gene was replaced by human SDC1 gene.

Mice

Il18-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il18em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00032
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

Mice

hIL12A

Strain Name：C57BL/6Smoc-Il12atm3(hIL12A)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000056
Validation Data：Presence

The endogenous mouse Il12a gene was replaced by human IL12A gene.

Mice

hTGFB1

Strain Name：C57BL/6Smoc-Tgfb1tm1(hTGFB1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200243

The endogenous mice Tgfb1 gene was replaced by human TGFB1 gene.

Mice

hHLA-DPB1*04: 01

Strain Name：C57BL/6Smoc-H2-Ab1tm1(hHLA-DPB1*04: 01)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210011
Validation Data：Presence

The endogenous mice H2-Ab1 gene was replaced by human HLA-DPB1*04:01 gene.

Mice

hMAPT

Strain Name：C57BL/6Smoc-Mapttm1(hMAPT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200116
Validation Data：Presence

The endogenous mouse Mapt gene was replaced by human MAPT gene.

Mice

App-KO

Strain Name：C57BL/6Smoc-Appem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190444

exon 3 of App gene was deleted to generate App knockout mice.

Mice

hIL4-Tg(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215004
Validation Data：Presence

These transgenic mice carry humanized IL4.

Mice

hCTLA-4(BALB/c)

Strain Name：BALB/cAnSmoc-Ctla4tm1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190078
Validation Data：Presence

Obtained by backcrossing of NM-HU-00014，hCTLA-4 mice.

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