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Mice

hPD-L1(2)/hCD28

Strain Name:C57BL/6JSmo-Cd274tm2(hPD-L1)Cd28tm2(hCD28)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210370

hPD-L1(2)(NM-HU-190039) was crossed with hCD28(NM-HU-190011)to generate hPD-L1(2)/hCD28 mice

Mice

hSERPINH1

Strain Name:C57BL/6JSmo-Serpinh1tm1(hSERPINH1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225081
Validation Data:Presence

The endogenous mouse Serpinh1 gene was replaced by human SERPINH1 gene.

Mice

Isl1-Dre

Strain Name:C57BL/6JSmo-Isl1em1(Dre-Wpre-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200177

A Dre-Wpre-polyA expression cassette was knocked into the Isl1 gene start codon site.

Mice

hIL21/hIL21R

Strain Name:C57BL/6JSmo-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220038
Validation Data:Presence

hIL21(NM-HU-200255) were crossed with hIL21R(NM-HU-210031) to generate hIL21/hIL21R mice.

Mice

Lepr-KO

Strain Name:C57BL/6JSmo-Leprem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

Pax7-IRES-Cre

Strain Name:C57BL/6JSmo-Pax7em1(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200120
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

hCTLA-4/hTIGIT

Strain Name:C57BL/6JSmo-Ctla4tm1(hCTLA4)Tigittm1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210399

hCTLA4(NM-HU-00014) was crossed with hTIGIT(NM-HU-00053) to generate hCTLA4/hTIGIT mice.

Mice

hF11

Strain Name:C57BL/6JSmo-F11tm1(hF11)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210015
Validation Data:Presence

The endogenous mice F11 gene was replaced by human F11 gene

Mice

Il33-KO(3)

Strain Name:C57BL/6JSmo-Il33em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210206

Il33-KO(3) mice(Stock No.NM-KO-210206) carry a knockout allele derived from the targeted deletion of exon 2. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(2) mice(Stock No.NM-KO-190436) carrying the exon 3-7 deletion.

Mice

H2/H2-K1-KO(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1h2em2H2-K1em2Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-NSG-006

Exon 2 of H2;H2-K1 gene was deleted to generate H2;H2-K1 knockout mice.

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