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Models

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Mice

Sst-IRES-Cre

Strain Name：C57BL/6Smoc-Sst1em1(IRES-Cre-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190091
Validation Data：Presence

A IRES-Cre-Wpre-polyA expression cassette was knocked into the Sst gene stop codon site.

Mice

Pax7-IRES-CreERT2

Strain Name：C57BL/6Smoc-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200099
Validation Data：Presence

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

Mice

hSERPINH1

Strain Name：C57BL/6Smoc-Serpinh1em1(hSERPINH1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225081
Validation Data：Presence

The endogenous mouse Serpinh1 gene was replaced by human SERPINH1 gene.

Mice

1300017j02Rik-KO

Strain Name：C57BL/6Smoc-1300017j02Rikem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190231
Validation Data：Absence

This 1300017j02Rik knockout mouse model was generated by knocking out the exon2-12 region of the 1300017j02Rik.

Mice

Aldh1L2-KO

Strain Name：C57BL/6Smoc-Aldh1L2em1Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

Exon 2 of Aldh1L2 gene was deleted to generate Aldh1L2 knockout mice.

Mice

Pdgfra-CreERT2

Strain Name：C57BL/6Smoc-Pdgfraem(CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225036
Validation Data：Presence

CreERT2 expression cassette was knocked into the Pdgfra gene .

Mice

Erbb2-Flox

Strain Name：C57BL/6Smoc-Erbb2em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220557
Validation Data：Absence

These mice carry loxP sites flanking exon 2 of Erbb2 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Erbb2 gene.

Mice

hIL13

Strain Name：C57BL/6Smoc-Il13em2(hIL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190069
Validation Data：Presence

The endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

Ube3a-KO

Strain Name：C57BL/6Smoc-Ube3aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200599
Validation Data：Absence

Exon 5 of Ube3a gene was deleted to generate Ube3a knockout mice.

Mice

Vip-IRES-Cre

Strain Name：C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200100
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.

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