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Models

About 43,982 results
Mice

C1qa-KO

Strain Name：C57BL/6Smoc-C1qaemSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210110
Validation Data：Absence

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

Mice

Apoa2-KO

Strain Name：C57BL/6Smoc-Apoa2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200035
Validation Data：Absence

Exon 3 of Apoa2 gene was deleted to generate Apoa2 knockout mice.

Mice

hCTLA-4/4-1BB

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18020
Validation Data：Absence

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCD3EDG/hCD19

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd3dem1(hCD3D)Cd3gem1(hCD3G)Cd19em1(hCD19)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220109
Validation Data：Presence

hCD3EDG(NM-HU-220120) mice were crossed with hCD19(NM-HU-00110) mice to generate hCD3EDG/hCD19 mice.

Mice

Tyro3-KO

Strain Name：C57BL/6Smoc-Tyro3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200558
Validation Data：Absence

Exon 3 of Tyro3 gene was deleted to generate Tyro3 knockout mice.

Mice

Krt14-2A-DreERT2

Strain Name：C57BL/6Smoc-Krt14em3(2A-DreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190125
Validation Data：Presence

A 2A-DreERT2 expression cassette was knocked into the Krt14 gene stop codon site.

Mice

hPD-1/hVISTA

Strain Name：C57BL/6Smoc-Visrem1(hVSIR)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000092
Validation Data：Absence

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

Mice

Acadvl-KO

Strain Name：C57BL/6Smoc-Acadvlem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200908
Validation Data：Absence

Exon 3-7 of Acadvl gene was deleted to generate Acadvl knockout mice.

Mice

hTNFa-Tg

Strain Name：C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200004
Validation Data：Presence

These transgenic mice harbor hTNFa promoter-hTNFa-pA expression cassette.

Mice

hIL9(BALB/c)

Strain Name：BALB/cAnSmoc-Il9em3(hIL9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220012
Validation Data：Presence

The endogenous mouse Il9 gene was replaced by human IL9 gene.

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