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Models

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Mice

hLYPD3

Strain Name:C57BL/6JSmo-Lypd3tm1(hLYPD3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200248

The endogenous mice Lypd3 gene was replaced by human LYPD3 gene.

Mice

A4gnt-KO

Strain Name:C57BL/6JSmo-A4gntem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201369

Exon 2-3 of A4gnt gene was deleted to generate A4gnt knockout mice.

Mice

A4galt-KO

Strain Name:C57BL/6JSmo-A4galtem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200001

Exon 3 of A4galt gene was deleted to generate A4galt knockout mice.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA-4

Strain Name:C57BL/6JSmo-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220070

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA4 mouse model was obtained by deleting sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1/hCTLA4(NM-HU-00079) mouse.

Mice

hICOSL(2)

Strain Name:C57BL/6JSmo-Icosltm3(hICOSLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000068
Validation Data:Presence

The endogenous mouse Icosl gene was replaced by human ICOSLG gene. While hICOSL(Stock No.NM-HU-00095) mice function similarly to hICOSL(2) mice,for more detailed information please contact our technical advisor.

Mice

Lrp1-Flox

Strain Name:C57BL/6JSmo-Lrp1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2101319

These mice carry loxP sites flanking exon 7-8 of Lrp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lrp1 gene.

Mice

hCTLA-4(2)

Strain Name:C57BL/6JSmo-Ctla4tm2(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

C1qa-KO

Strain Name:C57BL/6JSmo-C1qaemSmoc
Strain State:Repository Live | Cat. NO.:NM-KO-210110

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

Mice

Pax7-IRES-CreERT2

Strain Name:C57BL/6JSmo-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200099
Validation Data:Presence

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

Mice

hIL1RL1

Strain Name:C57BL/6JSmo-Il1rl1tm4(hIL1RL1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000067
Validation Data:Presence

The endogenous mouse Il1rl1 gene was replaced by human IL1RL1 gene.

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