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Models

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Mice

hCXCL13

Strain Name：C57BL/6Smoc-Cxcl13em1(hCXCL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225079
Validation Data：Presence

The endogenous mouse Cxcl13 gene was replaced by human CXCL13 gene.

Mice

hIL6ST

Strain Name：C57BL/6Smoc-Il6stem1(hIL6ST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204980
Validation Data：Absence

The endogenous mice Il6st gene was replaced by human IL6ST gene.

Mice

Ly6a-2A-Cre

Strain Name：C57BL/6Smoc-Ly6aem1(2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190028
Validation Data：Presence

A 2A-iCre expression cassette was knocked into the Ly6a gene stop codon site.

Mice

Ncr1-2A-CreERT2

Strain Name：C57BL/6Smoc-Ncr1em4(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200004
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Piezo1-CreERT2

Strain Name：C57BL/6Smoc-Piezo1tm2(CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18048
Validation Data：Absence

This tamoxifen-inducing Piezo1-CreERT2 tool mouse model was established by inserting a 2A-CreERT2 co-expression cassette into the Piezo1 gene stop codon site .

Mice

Krt5-2A-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190016
Validation Data：Absence

The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.

Mice

hMELTF

Strain Name：C57BL/6Smoc-Meltfem(hMELTF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215011
Validation Data：Presence

The endogenous mouse Meltf gene was replaced by human MELTF gene.

Mice

hPD-1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00103
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hTIM3(NM-HU-00054)to generate hPD-1/hTIM3 mice

Mice

Ncr1-2A-tdTomato

Strain Name：C57BL/6Smoc-Ncr1em(P2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215075
Validation Data：Absence

P2A-tdTomato expression cassette was knocked into the Ncr1 gene .

Mice

Myf5-Cre

Strain Name：C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200147
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

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