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Models

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Mice

hNECTIN4

Strain Name：C57BL/6Smoc-Nectin4tm1(hNECTIN4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210016
Validation Data：Presence

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

hIL23A(BALB/c)

Strain Name：BALB/cAnSmoc-Il23atm3(hIL23A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220013
Validation Data：Presence

The endogenous mouse Il23a gene was replaced by human IL23A gene.

Mice

Dmd-Q995X

Strain Name：C57BL/6Smoc-Dmdem1(Q995X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18026
Validation Data：Presence

These mice carry a p.Q995X mutation in Dmd gene.

Mice

Lrp1-Flox

Strain Name：C57BL/6Smoc-Lrp1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2101319

These mice carry loxP sites flanking exon 7-8 of Lrp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lrp1 gene.

Mice

Angptl6-KO

Strain Name：C57BL/6Smoc-Angptl6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201240

Exon 3 of Angptl6 gene was deleted to generate Angptl6 knockout mice.

Mice

hIL5-Tg(NMG,2)

Strain Name：NOD.Cg-PrkdcscidIl2rgem2Tg(hIL5)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220131
Validation Data：Presence

These transgenic mice carry humanized IL5.While hIL5-Tg(NMG)(Stock No.NM-KI-215005) mice function similarly to hIL5-Tg(NMG)(2) mice, for more detailed information please contact our technical advisor.

Mice

hCD3EDG/hCD19

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd19tm1(hCD19)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220109
Validation Data：Presence

hCD3EDG(NM-HU-220120) mice were crossed with hCD19(NM-HU-00110) mice to generate hCD3EDG/hCD19 mice.

Mice

Krt5-IRES-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200168
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Krt5 gene stop codon site.

Mice

hIL18

Strain Name：C57BL/6Smoc-Il18tm1(hIL18)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210038
Validation Data：Presence

The endogenous mice Il18 gene was replaced by human IL18 gene.

Mice

hPD-L1/hTIM3

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190056

hPD-L1(NM-HU-00062) was crossed with hTIM3(NM-HU-00054) to generate hPD-L1/hTIM3.

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