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Models

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Mice

Tlr5-CreERT2

Strain Name：C57BL/6Smoc-Tlr5em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215033
Validation Data：Presence

CreERT2 expression cassette was knocked into the Tlr5 gene.

Mice

hHER3

Strain Name：C57BL/6Smoc-Erbb3em1(hERBB3)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200234
Validation Data：Absence

The endogenous mice Erbb3 gene was replaced by human HER3 gene.

Mice

hCXCR6

Strain Name：C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215001
Validation Data：Presence

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

Mice

Tie1-2A-Cre

Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023
Validation Data：Absence

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

Mice

hIL31

Strain Name：C57BL/6Smoc-Il31em2(IL31)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200008
Validation Data：Presence

The endogenous mouse Il31 gene was replaced by human IL31 gene.

Mice

Csf2rb2-2A-Cre

Strain Name：C57BL/6Smoc-Csf2rb2em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210001
Validation Data：Presence

2A-Cre expression cassette was knocked into the Csf2rb2 gene. Csf2rb2 is also known as colony stimulating factor 2 receptor. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the modulation of memory.

Mice

hAPOE4

Strain Name：C57BL/6Smoc-Apoeem2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190002
Validation Data：Presence

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

Mice

hIL2RG

Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200007
Validation Data：Absence

The endogenous mouse Il2rg gene was replaced by human IL2RG gene.

Mice

R26-CreERT2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200041
Validation Data：Presence

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.

Mice

Il7r-Cre

Strain Name：C57BL/6Smoc-Il7rem1(Cre-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200306
Validation Data：Presence

Cre-Wpre-pA expression cassette was knocked into the Il7r gene start codon site.

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