Models

Metabolic Targets

SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.

mouse
Strain Name:C57BL/6JSmo-Pcsk9tm2(hPCSK9)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00075
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Ramp2tm(hRAMP2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-230044
mouse
Strain Name:C57BL/6JSmo-Ramp3tm(hRAMP3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-230045
mouse
Strain Name:C57BL/6JSmo-Ren1tm1(hREN)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220370
mouse
Strain Name:C57BL/6JSmo-Scaptm1(hSCAP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-232854
mouse
Strain Name:C57BL/6JSmo-Ttrtm1(hTTR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225087
mouse
Strain Name:C57BL/6JSmo-Ttrtm(hTTR-V50M)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220587
mouse
Strain Name:C57BL/6JSmo-Mefvtm1(hMEFV-V726A)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200221
Disease Connection:familial Mediterranean fever
mouse
Strain Name:C57BL/6JSmo-Tg(pAlb-hLPA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-225001
mouse
Strain Name:C57BL/6JSmo-Tgtn(pAlb-hLPA-3’UTR-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-231782
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