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Models

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Mice

hPD-1/hTLR9

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Tlr9 em1(hTLR9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190023
Validation Data:Absence

hPD-1(NM-HU-00015) was crossed with hTLR9(NM-HU-18016) to generate hPD-1/hTLR9.

Mice

Cpa3-2A-CreERT2

Strain Name:C57BL/6Smoc-Cpa3em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200005
Validation Data:Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Cpa3 gene stop codon site.

Mice

hSERPINC1

Strain Name:C57BL/6Smoc-Serpinc1em1(hSERPINC1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225075
Validation Data:Presence

The endogenous mouse Serpinc1 gene was replaced by human SERPINC1 gene.

Mice

Dmd-Q995X

Strain Name:C57BL/6Smoc-Dmdem1(Q995X)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18026
Validation Data:Presence

These mice carry a p.Q995X mutation in Dmd gene.

Mice

hIL1A

Strain Name:C57BL/6Smoc-Il1aem1(hIL1A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215071
Validation Data:Presence

The endogenous mouse Il1a gene was replaced by human IL1A gene.

Mice

Cela1-2A-DreERT2

Strain Name:C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190094
Validation Data:Presence

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

Mice

A4gnt-KO

Strain Name:C57BL/6Smoc-A4gntem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201369
Validation Data:Absence

Exon 2-3 of A4gnt gene was deleted to generate A4gnt knockout mice.

Mice

hPD-1/hCD3E

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd3eem1(hCD3E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18021
Validation Data:Absence

hPD-1(NM-HU-00015)was crossed with hCD3E(NM-HU-00114)to generate hPD-1/hCD3E。

Mice

A1cf-Flox

Strain Name:C57BL/6Smoc-A1cfem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Validation Data:Absence

These mice carry loxP sites flanking target exons of A1cf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A1cf gene.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA-4

Strain Name:C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Ctla4em1(hCTLA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220069
Validation Data:Absence

The Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA4 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hCTLA4(NM-HU-00014) mouse.

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