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Mice

Postn-2A-CreERT2

Strain Name：C57BL/6Smoc-Postnem(2A-CreERT2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225034

2A-CreERT2 expression cassette was knocked into the Postn gene .

Mice

Mcpt8-2A-CreERT2

Strain Name：C57BL/6Smoc-Mcpt8em1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200006
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Mcpt8 gene stop codon site.

Mice

Ifng-Venus-Luc

Strain Name：C57BL/6Smoc-Ifngem1(IRES-Venus-Luci)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18041
Validation Data：Presence

An IRES-Venus-Luci co-expression cassette was inserted in 3'UTR region of Ifng gene.

Mice

Col1a1-TRE3G-dCas9-VPR-EGFP

Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

Il12a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il12aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00024

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il12a.

Mice

Abcg8-KO

Strain Name：C57BL/6Smoc-Abcg8em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200906

Exon 3 of Abcg8 gene was deleted to generate Abcg8 knockout mice.

Mice

Nmu-2A-Cre

Strain Name：C57BL/6Smoc-Nmuem1(2A-Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200298
Validation Data：Presence

2A-Cre-WPRE-polyA expression cassette was knocked into the Nmu gene stop codon site. Nmu gene encodes a member of the neuromedin family of neuropeptides. The encoded protein plays a role in energy homeostasis and body temperature regulation. And the protein is homologous with human NMU, which is linked toobesity.

Mice

Abcb8-Flox

Strain Name：C57BL/6Smoc-Abcb8em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253536

These mice carry loxP sites flanking exon 3-6 of Abcb8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb8 gene.

Mice

hIL21R/hIL2RG

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Il2rgtm1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220004

hIL21R(NM-HU-210031) was crossed with hIL2RG(NM-HU-200007) to generate hIL21R/hIL2RG mice.

Mice

A26c3-Flox

Strain Name：C57BL/6Smoc-A26c3em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A26c3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A26c3 gene.

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