Rare diseases are those that affect only a small percentage of the world’s population. Most rare diseases are genetic. We provide many gene-engineered mouse models which are helpful for new therapies exploration and orphan drug development.
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Httem1Smoc 
                                            
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-226311                                             
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Hyal1em1Smoc 
                                            
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200990                                             
                                                                                            
                                                                                                        Disease Connection:mucopolysaccharidosis IX                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Idsem1Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200580                                             
                                                                                            
                                                                                                        Disease Connection:mucopolysaccharidosis II                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Iduaem1(flox)Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2107947                                             
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Iduaem/Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-230255                                             
                                                                                            
                                                                                                        Disease Connection:mucopolysaccharidosis I, otitis media                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Ins2em3(C96Y)Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-KI-190096                                             
                                                                                            
                                                                                                        Disease Connection:diabetes                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Kmt2btm1(flox)Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-190029                                             
                                                                                            
                                                Research Application:Epigenetic                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Latem1(Y136F)Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-KI-200249                                             
                                                                                            
                                                                                                        Disease Connection:IgG4-related disease                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Ldlrem1Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-KO-210198                                             
                                                                                            
                                                                                                        Disease Connection:familial hypercholesterolemia, fatty liver disease                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Lmnatm1(G609G)Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-KI-200284                                             
                                                                                            
                                                                                                        Disease Connection:progeria                                                 
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