Rare diseases are those that affect only a small percentage of the world’s population. Most rare diseases are genetic. We provide many gene-engineered mouse models which are helpful for new therapies exploration and orphan drug development.
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Glaem1Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-KO-200601                                             
                                                                                            
                                                                                                        Disease Connection:Fabry disease                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Gnastm1(flox)Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200300                                             
                                                                                            
                                                                                                        Disease Connection:pseudohypoparathyroidism                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Gnsem1Smoc 
                                            
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201161                                             
                                                                                            
                                                                                                        Disease Connection:mucopolysaccharidosis III                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Gpr143em1Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200980                                             
                                                                                            
                                                                                                        Disease Connection:ocular albinism                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Grhprem1Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-210151                                             
                                                                                            
                                                                                                        Disease Connection:primary hyperoxaluria type 2                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Hbb-bsemHbb-btem1Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-KO-234923                                             
                                                                                            
                                                                                                        Disease Connection:Beta thalassemia                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc 
                                            
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000033                                             
                                                                                            
                                                Research Application:Immunotherapy,drug screening                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-HU-2000080                                             
                                                                                            
                                                Research Application:Thalassemia research;drug screening                                                 
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Sncaem(hSNCA)Smoc 
                                            
                                                Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220261                                             
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                                                Mice
                                             
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                                         Strain Name:C57BL/6Smoc-Tgtn(pPrp-hTDP-43 A315T)1Smoc 
                                            
                                                Strain State:Repository Live | Cat. NO.:NM-KI-234659                                             
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